Deep venous thrombosis and pulmonary embolism is a frequent medical problem that is seen everyday life. It affects about million patients every year in United States.
The deep venous thrombosis is a formation of blood clot most commonly in the leg and pelvic veins.
The frequent risk factors for deep venous thrombosis include pregnancy, birth control pills (estrogens), prolonged immobilization after trauma or surgeries and medical illness.
DVT causes damage to the patient in 2 different ways
The clot can dislodge from the legs and move to the lungs and this is called pulmonary embolism and this disorder kills 100-300,000 patient's every year. The second most common complication his the clot remains in the vein and causes the permanent damage to the vein thus causing problems to the chronic drainage from leg to the heart making the leg swell and creating a venous stasis ultimately forming venous ulcer and disabling the patient from being active throughout their life. This is called post phlebitic syndrome.
The current treatment for deep venous thrombosis include in his tissue and of blood thinners including Warfarin and Xaralto. These drugs are very effective in preventing propagation of clot and sometimes preventing this clot to dislodge from the leg to the lungs, however this treatment is fundamentally flawed as it does not dissolve the clot.